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Your brain may be wired to regain lost weight

Weight loss is not simply a test of willpower. The human brain evolved to protect body fat during times of scarcity, and it can treat a previously higher weight as the new normal, triggering stronger hunger, cravings, and lower energy use after weight loss. This biological “memory” helps explain why many people regain weight after dieting and why medications such as Wegovy and Mounjaro can help by reducing appetite signals, although their effects may fade when treatment ends.

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A profile illustration of a human head showing a detailed, reddish-orange brain. AI-written description A generic or stock image — The image is a digital illustration of a brain, which is related to the headline's topic of the brain, but the description is not specific enough to confirm it depicts the event described.
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